Marc Pfister

Prof. Dr. med.
Marc Pfister

Position(s)
Deputy Chief Physician Paediatric Pharmacology

Institution
University Children's Hospital Basel

Phone +41 61  704 12 12

Email

Research Group Marc Pfister

 

Research Focus

Clinical Pharmacology

Area of Research

Apply pharmacometric and systems pharmacology computer models to characterize effects of development and disease on therapeutics with the goal to individualize and optimize the use of medicines in neonates, infants and children. Investigate interplays between growth, kidney function, dialysis treatment, and pharmacotherapy. Develop AI based bedside digital health solutions such as clinical decision support tools to benefit sick children and their caregivers. Lead SwissPedPha, Swiss center for pharmacology and pharmacometrics research.


Approved Research Projects

  • Pharmacology study to characterize protein binding in infants and children
  • Pharmacology study to investigate pharmacokinetics and dosing of metamizole in infants
  • and children
  • Thy-Mod study to personalize dosing in children with hyper- or hypothyroidism
  • Physical activity study to personalize insulin therapy in children with type-1 diabetes mellitus
  • EPIC study to investigate copeptin and renal biomarkers in dehydrated infants and children
  • KidMaCare study to investigate novel renal biomarkers in healthy infants and children and those with cancer

    Collaborations

    National Collaborations

    • ETH Basel/Zurich
    • Universities of Zurich, Berne, Lausanne and Geneva
    • Leadership roles in national initiatives and projects such as SwissPedNet, SwissPedDose and SwissPedPha


    International Collaborations

    • University of Yale (Nephrology)
    • University of Stanford (Nephrology)
    • University of Florida (Pharmacometrics and Pharmacology)
    • University of Constance (Mathematics)
    • University of Regensburg (Neonatology)

    Ongoing Research Projects

    Pharmacometric and pharmacology research projects to personalize treatment/dosing in preterm- and term neonates, children with type 1 diabetes mellitus, children with hypo- or hyperthyroidism as well as children receiving renal replacement treatment.

    Pharmacology research projects to investigate use of novel markers to monitor glomerular and tubular kidney function in neonates, infants and children.


    Research Team

    Jantine Brussee, PhD

    Postdoc Fellow and Pharmacometrician

    Phone +41 61 704 12 12
    Email

    Verena Gotta, PharmD PhD

    Senior Research Fellow and Pharmacist

    Phone +41 61 704 12 12  
    Email

    Freya Bachmann, MSc

    PhD Student

    Phone -
    Email

    Julia Bielicki, MD MPH

    Research Fellow

    Phone +41 61 704 12 12  
    Email

    Michael Büttcher, MD

    Research Fellow

    Phone +41 61 704 12 12
    Email

    Sarah Koechlin

    Project Manager PharmD MPH

    Phone +41 61 704 12 12
    Email

    Linda Stamm

    Study Nurse

    Phone +41 61 704 12 12  
    Email

    Stephanie Leroux, MD PhD

    Postdoc Fellow, Neonatologist and Pharmacometrician

    Phone +41 61 704 12 12  
    Email

    Andrew Atkinson, PhD

    Postdoc Fellow and
    Biostatistician

    Phone +41 61 704 12 12  
    Email

    Mirjam Pfiffner, PharmD

    PhD Student

    Phone -  
    Email

    Malte Kohns, MD

    Research Fellow

    Phone +41 61 704 12 12
    Email

    Ricarda Foulk

    Project Manager

    Phone +41 61 704 12 12  
    Email

    Regina Santoro

    Study Nurse

    Phone +41 61 704 12 12  
    Email

    Gilbert Koch, PD

    Senior Research Fellow and Mathematician

    Phone +41 61 704 12 12 
    Email

    Tamara van Donge, MSc

    PhD Student

    Phone +41 61 704 12 12
    Email

    Tatjana Welzel, MD

    Research Fellow

    Phone +41 61 704 12 12 
    Email

    Victoria Ziesenitz, MD

    Research Fellow

    Phone +41 61 704 12 12
    Email

    Claudia Werner

    Study Nurse

    Phone +41 61 704 12 12  
    Email

    Aurora Frei

    Study Nurse

    Phone +41 61 704 12 12  
    Email