Hendrik Scholl

Prof. Dr. med.
Hendrik Scholl

Position(s)
Head of Department Ophthalmology

Institution
University Hospital Basel

Phone
+41 61 265 90 59

Email

Research Group Hendrik Scholl

 

Research Focus

Neurology

Area of Research

Diagnosis and therapy of retinal diseases, especially monogenic and genetically complex macular and retinal degenerations. Outcome measures for intervention studies. Functional (clinical electrophysiology and psychophysics) and morphological (retinal imaging) characterization; Genotype-phenotype correlation


Approved Research Projects

  • The ProgStar Study (The Natural History of the Progression of Geographic Atrophy Secondary to Stargardt’s Disease)
  • The SMART Study (Scotopic Microperimetric Assessment of Rod Function in Stargardt Disease; ancillary study to the ProgStar Prospective Study)
  • The ProgStar-4 Study (The Natural History of the Progression of Atrophy Secondary to Stargardt Disease Type 4 (STGD4): A Prospective Longitudinal Observational Study of STGD4, a PROM1-Related Macular Dystrophy)
  • Ocular Albinism: Structure-Function Correlation of the Central Retina, Phenotype-Genotype Correlation and Interventional Therapy to Improve Visual Performance


    Collaborations

    National Collaborations

    • Novartis Institutes for Biomedical Research (NIBR)
    • Friedrich Miescher Institute for Biomedical Research, Basel
    • OCT research group for OCT technology, Virtual Ophthalmology, Artificial Intelligence (AI) and Robotics of the Department of Ophthalmology at the University of Basel
    • Retina Suisse

    International Collaborations

    • European Network of Clinical Research in Ophthalmology
    • Retina International
    • PRO RETINA Deutschland e. V.
    • Foundation Fighting Blindness
    • European Vision Institute EEIG
    • ProgStar study group
    • Wellcome Trust
    • Bertarelli Foundation
    • Spectrum Foundation
    • Chan Zuckerberg Initiative
    • Moorfields Eye Hospital

    Ongoing Research Projects

    • PINNACLE: Deciphering AMD by deep phenotyping and machine learning
    • GABiE: A biomarker evaluation study in patients with geographic atrophy secondary to agerelated macular degeneration (AMD) evaluating the use of microperimetry (fundus-controlled perimetry) and Swept Source-OCT in assessing changes in retinal sensitivity and anatomy over time
    • AIRM: A Staged Study Incorporating a Phase 1b, Multicenter, Unmasked, Dose Escalation Evaluation of Safety and Tolerability and a Phase 2, Multicenter, Unmasked, Randomized, Parallel-Group, Controlled, Proof of Concept Investigation of Efficacy and Safety of ASP7317 for Atrophy Secondary to Age-related Macular Degeneration

    Research Team

    Prof. Dr. med.
    Christian Prünte

    Leader Clinical Trial Center

    Phone +41 61 265 86 74
    Email

    Daniela Hauenstein

    Study Coordinator

    Phone +41 61 265 87 18
    Email

    Dr. med. Ghislaine Traber

    Investigator

    Phone +41 61 265 78 88
    Email

    Nils Schärer, BSc

    Study Nurse

    Phone +41 79 139 39 28
    Email

    Dr. med. Bence György, PhD

    Investigator

    Phone +41 61 265 92 43
    Email

    Ursula Hall, MSc

    Study Nurse

    Phone +41 79 172 92 48
    Email