Christ-Crain

Prof. Dr. med.
Mirjam Christ-Crain

Position(s)
Deputy Chief Endocrinology
Co-Head Department of Clinical Research

Institution
University Hospital Basel

Phone +41 61 328 70 80

Email

 

Research Focus

Endocrinology, Metabolism & Divelopmental Disorders

Area of Research

Water and electrolyte disorders, in particular diagnosis and therapy in polyuria and polydipsia syndrome and hyponatremia.
Corticosteroids and other stress hormones for outcome prediction of various diseases and as immunomodulatory treatment.


Approved Research Projects

CARGOx study (Copeptin after arginine infusion compared to copeptin after hypertonic saline infusion for the differential diagnosis of diabetes insipidus)

SANDx study (SGLT-2 inhibitors for treatment of SIADH, a placebo-controlled randomised study)

Glucacop (Glucagon for the differential diagnosis of Diabetes insipidus, a randomized placebo-controlled trial)

FERTIL (IL-1 antagonism for patients with PCOS)


Collaborations

National Collaborations
- Prof. Beat Müller and Prof. Philipp Schütz, Kantonsspital Aarau
- Prof. Christoph Henzen, Kantonsspital Luzern
- PD. Dr. Stefan Bilz, Kantonsspital St.Gallen
- Prof. Felix Beuschlein, Universitätsspital Zürich
- Prof. Nelly Pitteloud, Universitätsspital Lausanne (CHUV)

International Collaborations
- Prof. Willem Jan Bos, Nieuwegein Hospital (the Netherlands)
- Prof. Martin Fassnacht, Universitätsspital Würzburg
- PD Dr. Wiebke Fenske, Universitätsspital Leipzig
- Prof. Antonio Ribeiro Jr., Belo Horizonte, Brazil
- Prof. Ewout Hoorn, Rotterdam University Hospital
- Prof. Volker Burst, Uniklinik Köln 
- Prof. Alessandro Peri, Florence 
- Prof. Mark Sherlock and Prof. Chris Thompson, Beaumont Hospital Dublin
- Prof. Darko Kastelan, University Hospital Centre Zagreb,Croatia


Ongoing Research Projects

GOLD study (Effects of GLP-1 analogues on fluid intake in patients with primary polydipsia): randomized placebo-controlled cross-over study evaluating the effect of GLP-1 analogs on fluid intake in patients with primary polydipsia

HIT study (Hyponatremia Intervention study)

COMEN study (Copeptin in monosymptomatic enuresis nocturna): observational study evaluating copeptin as a predictor for treatment response in children with monosymptomatic enuresis nocturna.

EMPOWER (SGLT-2 Inhibitoren bei eu-und hypervolämer Hyponatriämie, a randomized placebo-controlled trial)

OxyMa (MDMA to stimulate oxytocin levels in diabetes insipidus, a randomized placebo-controlled trial)


Research Team

Cemile Barthelt

Leading Study Nurse
DAS Clinical Trial Practice and Management

Phone +41 61 556 53 04

Email

Dr. med. Julie Refardt

Co-leader of research group
Senior Physician

Phone +41 61 328 76 08

Email

Publications

Nicole Salvisberg

Scientific Administrative Assistant

Phone +41 61 328 51 20

Email

Lara Gut

Research fellow

Phone +41 61 328 60 61

Email

Nina Hutter

Senior Study Nurse
CAS Clinical Research I

Phone +41 61 328 68 26

Email

Dr. med. Bettina Winzeler

Co-leader of research group
Senior Physician

Phone ---

Email

Publications

Sophie Monnerat

MD PhD Student

Phone +41 61 328 76 08

Email

Brida Caviezl

Research fellow

Phone +41 61 328 54 37

Email

Joyce Santos de Jesus

Study Nurse


Phone +41 61 328 50 91

Email

Dr. med. Laura Potasso

Senior Research Fellow
 

Phone +41 61 328 58 76

Email

Publications

Cihan Atila 

MD PhD student

Phone +41 61 328 58 81

Email

Sophia Lengsfeld

Research fellow

Phone +41 61 328 68 14

Email