Clinical Research Day 2021

On 28 January 2021, the Department of Clinical Research (DKF) kicked off this year's research year - due to the current pandemic situation as a webinar.

The inspiring keynote lecture delivered by Prof. Ulrich Dirnagl, Director of the QUEST Center for Transforming Biomedical Research at the Berlin Institute of Health and Director of the Department of Experimental Neurology at the Charité, on the topic of "Improving the value of biomedical research: Lessons learned from COVID-19" was followed by 175 visitors.

Subsequently, young researchers at the DKF presented an impressive cross-section of the clinical research landscape. The best presentations were casted by audience voting.

Congratulations to all award winners

Best oral presentations

1st prizeFabienne DecrueImpact of air pollution on lung function in preterm and term born infants; a birth cohort study
2nd prizeMilica PopovicEffects of Interleukin-1 Antagonism on Hyperandrogenemia in Women with Polycystic Ovary Syndrome
3rd prizeLuca Köchlin0/2h-Algorithm using High-Sensitivity Cardiac Troponin I in the Diagnosis of Myocardial Infarction

Best rapid fire presentations

1st prizeAnnina VischerBlood pressure control through monotherapy in treatment-naive patients with arterial hypertension
2nd prize

Anna-Chiara Schaub

Valerian Altersberger

Potential of a short-term, high-dose probiotic supplementation as adjuvant therapy in depression

Maintenance of Acute Stroke Care Service during the COVID-19 pandemic lockdown


Mirjam Christ-Crain and Christiane Pauli-Magnus, Co-Directors DKF


Keynote Lecture
Improving value of biomedical research: Lessons learned from COVID-19
Prof. Ulrich Dirnagl, Charité Berlin
Chair: Lars Hemkens, DKF

12.20Session 1 - Oral Presentations

Systematic screening on admission for SARS-CoV-2 to detect asymptomatic infections, Rahel Stadler

Risk of non-AIDS and AIDS defining malignancies of early versus deferred antiretroviral initiation, Frederique Chammartin

Effects of Interleukin-1 Antagonism on Hyperandrogenemia in Women with Polycystic Ovary Syndrome, Milica Popovic

COVID-evidence: a living platform to improve COVID-19 research and collaboration, Perrine Janiaud

Chairs: Roland Buhl and Maria Pia Sormani, members of the DKF Scientific Advisory Board
13.10Session 2 - Oral Presentations

0/2h-Algorithm using High-Sensitivity Cardiac Troponin I in the Diagnosis of Myocardial Infarction, Luca Köchlin

Optical Coherence Tomography as a marker of Neuronal Loss and Disability in Multiple Sclerosis, Nuria Cerda Fuertes

AURORA - a 3D model guided fresh frozen section study in nerve sparing radical prostatectomy, Christian Engesser

Impact of air pollution on lung function in preterm and term born infants; a birth cohort study, Fabienne Decrue

Chairs: Markus Zabel and Marco Valgimigli, members of the DKF Scientific Advisory Board
14.00Audience voting

Session 3 - Rapid Fire Presentations

Post Intensive Care Syndrome in out-of-hospital cardiac arrest patients, Alessia Vincent

Barrett oesophagus and reflux-esophagitis five years after LSG and LRYGB, Bettina Wölnerhanssen

Blood pressure control through monotherapy in treatment-na‹ve patients with arterial hypertension, Annina Vischer

Maintenance of Acute Stroke Care Service during the COVID-19 pandemic lockdown, Valerian Altersberger

Potential of a short-term, high-dose probiotic supplementation as adjuvant therapy in depression, Anna-Chiara Schaub

Development of a risk-based trial management and central monitoring concept, Katharina Klatte

Intrathecal Immunoglobulin M synthesis is associated with higher disease activity and severity in MS, Johanna Oechtering

Findings consistent with subclinical vasculitis in patients with new onset polymyalgia, Daniele Gozzoli

Chair: Matthias Briel, DKF

14.40Audience voting
14.45Award ceremony
Best short presentations and Rapid Fire presentations
14.50Concluding remarks
Steffen Eisenhardt
Chair of the DKF Scientific Advisory Board

Download program

Organising Committee

Mirjam Christ-Crain, Co-Director DKF
Christiane Pauli-Magnus, Co-Director DKF
Matthias Briel, Attending Physician DKF
Lars Hemkens, Senior Scientist DKF



Regina Mattmüller
Head of Secretariat
Tel +41 61 328 77 17

Further submitted research projects

Research AreaTitle, First Author(s)

Sex differences of vascular brain lesions in patients with atrial fibrillation, Selinda Ceylan

A comprehensive secondary prevention benchmark (2PBM) score identifying differences in secondary prevention care in patients after acute coronary syndromes (ACS), Matthias Haegele, Yu-Ching Liu

Impaired heart rate variability triangular index to identify clinically silent strokes in patients with atrial fibrillation, Peter Hämmerle

Sex-specific differences in adverse outcome events among patients with atrial fibrillation, Simone Evers-Dörpfeld


Prevalence and risk factors for psychological burden in COVID-19 patients and their relatives: A prospective observational cohort study, Katharina Beck, Alessia Vincent

The impact of brief written leadership instructions on leadership behaviour and team performance in resuscitation teams: a prospective observational simulator-based study, Haron Haude

Interventions Facilitating Cancer Predisposition Cascade Genetic Screening and Family Communication, Vasiliki Baroutsou

Implementing a digital platform to support family communication about hereditary cancer risks, Monica Aceti


Impact of nocturnal hypoglycemia on cardiac repolarization in children with diabetes, Sara Bachmann

Effect of D-allulose on satiation hormone response, glycemic control and gastric emptying: a randomized, controlled trial, Fabienne Teysseire

Calculated osmolality is underestimating osmolality changes in children with diabetic ketoacidosis: an observational study, Marie-Anne Burckhardt

Genetic councelling

Genetic Testing and Surveillance of Young Breast Cancer Survivors and Blood Relatives: A Cluster Randomized Trial, Maria Katapodi

Effect of genetic consultation on genetic literacy: a 15 years investigation in two countries, Carla Pedrazzani

Infectious Diseases

First Report of a Cluster of Extended-Spectrum Beta-Lactamase Producing Klebsiella pneumoniaeSequence Type 101 Isolated from Food and Humans, Losandra Aguilar-Bultet

Unraveling Sources and Transmission Pathways of Extended-Spectrum Beta-Lactamase Producing Enterobacterials - a On-Health Approach, Lisandra Aguilar-Bultet

Tuberculosis disease in asymptomatic children: clinical characteristics in a 1 low-incidence country, Nora Fritschi


Oral Anticoagulants in Atrial Fibrillation Patients with Recent Stroke who are Dependent on the Daily Help of Others, Louisa Meya, Alexandros A Polymeris

Comparative analysis of dimethyl fumarate and teriflunomide in relapsing remitting multiple sclerosis, Jannis Müller, Sabine Schädelin

Impact of the COVID-19 Outbreak on Acute Stroke Treatment in Switzerland, Gian Marco De Marchis

Serum levels of neurofilament light chain are inversely associated with renal function in an elderly cohort, Alexandros Polymeris

High frequency and intensive prevention program for cognitive stabilization and improving of quality of life in Parkinson’s disease patients, Ketevan Toloraia

Genetic proxies for PCSK9 inhibition associated with lower lipoprotein(a): effects on coronary artery disease and ischemic stroke, Tolga D. Dittrich

Endovascular Treatment versus Best Medical Treatment for Ischemic Stroke with Large Vessel Occlusion in the 6–24 Hour Window among Non-DAWN-Non-DEFUSE Patients, Tolga D. Dittrich

Evaluation of cognitive subtypes in Parkinson’s Disease - Correlations with qEEG power spectra, Selina Beltrani

Training Effects in Smartphone-Based Tests of Cognition, Dexterity & Mobility in Multiple Sclerosis, Tim Wölfle

Global cortical atrophy is associated with an unfavorable outcome in anticoagulated stroke patients, Annaelle Zietz, Martha Kubacka

The cognitive course in Parkinson’s disease patients treated with Deep Brain Stimulation of subthalamic nucleus – Correlations with qEEG, Antonia Meyer

Effect of admission time on prevention of acute stroke treatment at Stroke Units ans Strike Centers in Switzerland, Valerian Altersberger


Time to Readmission is Increased in Voluntary and Compulsory Psychiatric Inpatients with a Therapeutic Leave, Tiziana Ziltener

Guidance of antidepressant treatment with the biomarker prefrontal theta cordance in REM sleep, Thorsten Mikoteit


Mortality and outcome of patients over 80 years surgically treated for chronic subdural hematoma, Alessio Chiappini

Knee biomechanics of single leg hop landings after primary anterior cruciate ligament repair and InternalBraceTM augmentation, Brite Coppers


Establishing prediction intervals for the SpeedWheel acuity test, Anja Palmowski-Wolfe

Regulation of Pupil Size Under Real-World Conditions, Rafael Lazar

Thrombopoietin-receptor agonist-immunomodulation in young and midlife adult primary immune thrombocytopenia (ITP): A multi-center open label trial with romiplostim (iROM), Alexandra Schifferli

A randomised prospective study comparing 2D 4K vs 3D 4K laparoscopic imaging systems in a pelvitrainer model, Tibor Zimpfer

Metabolic monitoring in children during diabetic ketoacidosis via breath-analysis, Mo Awchi

Planned subgroup analyses in randomized clinical trials: A comparison between early 2000s, 2012 and 2016, Ala Taji Heravi

Enriching medication review with a pharmacogenetic profile - a case of tamoxifen ADRs, Chiara Jeiziner

Modeling multi-center rare disease data: application to congenital hypothyroidism in newborns, Britta Steffens

Are salivary cytokines biomarkers in oncological and infectiuos diseases? - A systematic review, Tamara Diesch