Research Focus

Neurology

Area of Research

Development, standardisation and digitisation of clinical rating scales for recording and quantifying neurological symptoms, including algorithm-based feedback systems. The focus is on neuroimmunological (MS, NMOSD) and neurodegenerative (Huntington's disease) disorders. Further, development of telemedical applications in neurology for assessing clinical symptoms; to perform physical examination in home environment (to compensate for reduced mobility, pandemic and planning DCTs). In addition, use of AI-based methods to analyse the data obtained from the systems we develop. Further implementing new strategies in QMS and supporting validation of software used in the medical field. 

2017-2019 "Development of an eEDSS App"; research grant from Fonds zur Förderung von Innovations-Transfer Universitätsspital Basel

2017-2019 "Evaluation of the reliability and validity of the Modified Manual Muscle Test for persons with MS"; (co-applicant) research grand from the Swiss Multiple Sclerosis Society

2011-2013 "Development and validation of an electronic data capturing system for EDSS assessments in MS: Neurostatus e-Scoring"; research grant form MS-Fonds, Department of Neurology, University Hospital Basel 

2010-2012 "Characterization of lymphocyte subsets in patients with MS treated with oral fingolimod"; research grand from the Swiss Multiple Sclerosis Society

2007-2013 "Development of electronic / audiovisual and web-based teaching and certify-cation tools for Training of Neurologists in international therapeutic studies in MS"; research grant form MS-Fonds, Department of Neurology, University Hospital Basel 

National Collaborations

- Innovation Management Basel USB

- FHNW Muttenz Life Sciences und Wirtschaftsinformatik

International Collaborations

- Research Group of Prof. F. Paul, Experimental and Clinical Research Center (ECRC), Charité Universitätsmedizin, Berlin, Germany

- Matthew Johnson, Microsoft Research, Cambridge, United Kingdom

"Development and validation of a video-assisted assessment comparing HCPs with Neurologists to capture disability in MS, the Neurostatus-SMARTCARE"; collaborative research project with RC2NB, supported by Novartis Pharma AG (ethic approval given)

"Digitalisation and standardisation of the dataflow at the outpatient clinics; eCapture – a pilot project"; collaborative research project with ICT at the University Hospital Basel (in planing stage)

"Development of an e-learning platform”; research grant from Roche, Merck and Sanofi (in planing stage)

“Development of a new clinical progression marker in MS”; research grant form Novartis Pharma AG (ethic approval given)

2013 - paused; "Validation of a Kinect-based Motion Capturing device for a quantitative analyse of disability in MS";  Collaborative research project with Microsoft research Cambridge, UK, and support from Novartis Pharma AG (ethic approval given)