27 June 2023
SNF IICT Call 2023: Three studies from the USB receive funding
The DKF research groups of Mirjam Christ-Crain, Jehuda Soleman and Ivan Martin have each been awarded an Investigator-Initiated Clinical Trial (IICT) grant from the Swiss National Science Foundation (SNSF). This year, a total of seven studies recieve this funding. They are considered to be of particular importance for patients from a medical and social point of view..
Project leader Prof. Dr. med. Mirjam Christ-Crain, Deputy Chief of Endocrinology, Diabetes and Metabolism, University Hospital Basel
OxyTUTION study
Oxytocin substitution therapy in patients with central diabetes insipidus: a double-blind randomized-controlled trial the OxyTUTION trial
Direction
Prof. Dr. med. Mirjam Christ-Crain, Dr. med. Cihan Atila, Dr. med. Svenja Leibniz, Prof. Dr. med. Dominique de Quervain, Prof. Dr. med. Matthias Liechti
Study design
Randomised, placebo-controlled, double-blind phase II study
Study objective
To investigate the effects of intranasally administered oxytocin on psychological symptoms and socio-emotional deficits in patients with diabetes insipidus
Number of planned study sites
4-5
Number of study participants
112
Project duration
5 years
DKF support
Methodological consulting, Consulting on Patient & Public Involvement (PPI), Statistics, Data Management, Monitoring
Project leader PD Dr. med. Jehuda Soleman, Senior Physician Neurosurgery, University Hospital Basel
EMINENT-ICH study
Early Minimally INvasive image-guided ENdoscopic evacuaTion of IntraCerebral Haemorrhage: a randomized controlled trial
Direction
PD Dr. med. Jehuda Soleman, Prof. Dr. med. Raphael Guzman, Dr. med. Tim Hallenberger
Study design
Randomised-controlled, non-blinded superiority trial
Study objective
To evaluate the efficacy of early minimally invasive surgical hematoma evacuation in patients with intracerebral hemorrhage
Number of planned study sites
11
Number of study participants
200
Project duration
5 years
DKF support
Methodological consulting, Consulting on Patient & Public Involvement (PPI), Statistics, Data Science, Monitoring
Project leader Prof. Dr. Ivan Martin, Head of Research Group DBM Tissue Engineering, Head of Innovation Focus Regenerative Surgery, University Hospital Basel
PFOA II study
Treatment of patellofemoral osteoarthritis with nasal chondrocyte-based engineered cartilage(N-TEC) implantation in a randomized, controlled, multi-center phase II clinical trial
Direction
Prof. Dr. Ivan Martin, PD Dr. med. Marcus Mumme, Prof. Dr. Andrea Barbero
Study design
Prospective randomised-controlled phase II study
Study objective
To investigate the efficacy of treatment of patellofemoral osteoarthritis (PFOA) with nasal chondrocyte-engineered cartilage (N-TEC)
Number of planned study sites
7
Number of study participants
75
Project duration
5 years
DKF support
Methodological consulting, Statistics, Data Management, Monitoring