ICARO-Studie
7 November 2025

Persistent lymph node involvement in breast cancer after chemotherapy: surgical removal is not always indicated

Affected lymph nodes in the armpit are usually the first sign that a breat cancer disease has spread. Many patients therefore receive chemotherapy before surgery. If this does not eliminate the lymph node involvement, the answer often is a large-scale excision of the armpit. A new study investigated whether this radical surgical procedure is really necessary if only isolated tumor cells are still detectable in the armpit lymph nodes.


 

News archive

N. Labhardt

1 November 2022

"Research with significance", "Relevance to clinical practice", "Change and impact as a goal" - these are guiding principles with which Niklaus Labhardt describes his vision for the tasks newly entrusted to him at the University of Basel and the University Hospital Basel.

Biomarker Lab

31 October 2022

For the third time in a row, Jens Kuhle, Head of Multiple Sclerosis Centre at the University Hospital Basel and DKF/DBM research group leader, is awarded an SNF project grant for the development of biomarkers for the detection and prognosis of disease activity in multiple sclerosis (MS) on a personalised level.

PPI Video Screenshot

3 October 2022

Applications for the Investigator-initiated Trials (IICT) funding program must include a plan for the active involvement of patients throughout the study. Project applications such as that for the EMINENT-ICH study are now supported with a "Preparatory Grant".

COPD

30 September 2022

A comprehensive Lancet Commission publication, co-authored by research group leader Prof. Daiana Stolz, presents core strategies for preventing chronic obstructive pulmonary disease and combating it worldwide.

ischaemic brain stroke

20. September 2022

A large international observational study provides convincing evidence that an early start with the administration of direct oral anticoagulants makes sense

Pituitary Gland

15 September 2022

Diabetes insipidus from a patient's perspective

For the first time, a large-scale, international patient survey provides important insights into the diagnosis and treatment as well as treatment-related side effects and psychological concomitant diseases of this rare neuroendocrine disease

RDLM

1 September 2022

The DKF actively participates in the Data Stewardship Program of the University of Basel. This initiative promotes sustainable ways of collecting, using and sharing of data as well as the establishemnt of efficient data management planning. The DKF contributes its unique experience in handling sensitive personal data.

 

19 July 2022

Human research is more than classic clinical trials can cover. A new DKF training explains the different legal requirements for the numerous types of possible research projects.

 

iict2022

24 June 2022

Congratulations to the DKF research groups led by PD Dr. Elisabeth Kappos and PD Dr. Özgür Yaldizli. The Swiss National Science Foundation SNSF has awarded two of the prestigious Investigator-initiated Clinical Trials (IICT) grants to the Basel researchers. The two projects are convincing, among other things, due to their innovative study design and exemplary inclusion of patients in the project planning.

KnowHow

1 June 2022

Using the recruitment of study participants as an example, the DKF research group of Matthias Briel shows how results from meta-research can be used in practical study planning.

Meta-research is a competence focus at DKF. This discipline strives for evidence-based improvement of research and subsequently of health care.

Ivana & Sina

2 May 2022

The IRASPEN registry is to provide answers to a special form of psoriasis that has hardly been researched to date. The DKF supports the coordination of the international data collection.

Over a period of 5 years, Alexander Navarini's research group, together with 14 other centres in ten countries, will investigate the clinical course and response to already established treatments of "psoriasis pustulosa".

Icons Banner 2

25 May 2022

Study teams with a small budget can also benefit from the support offered by DKF Scientific Services.

In order to be able to support all research groups efficiently, a number of free- of-charge offers are available thanks to financial grants from the Medical Faculty Basel and, to some extend, via job transfers from the University Hospital Basel. In addition, the possibilities for low-threshold assistance have recently been greatly expanded.

swissaf video vimeo

4 April 2022

Silent cerebral infarcts are associated with impaired cognitive function

Prof. Michael Kühne, Head of the Atrial Fibrillation Clinic at the USB, and Michael Coslovsky (DKF) explain the study in a video.

kuhle, benkert

1 March 2022

The blood marker "neurofilament light chain" can significantly improve therapy decisions in multiple sclerosis.

Prof. Jens Kuhle, head of the Basel MS Center, and Pascal Benkert of DKF explain the relevance of their recently published study in "The Lancet Neurology" in an interview.

Annemarie Karrasch Award 2022

15 February 2022

Prof. Viola Heizelmann-Schwarz is awarded by the propatient foundation for her multicenter MATAO study in advanced ovarian cancer.

The foundation particularly honors research and innovation projects that can demonstrate a high direct benefit for affected patients.

REDCap

2 February 2022

White Paper

29 November 2021

Staphylococcus Aureus

1 November 2021

Paris, Pauli-Magnus

2 November 2021

p-value

5 October 2021

Study Center Tanzania

1 September 2021

Brain CT

13 July 2021

Niels Schärer & Daniel

5 July 2021

Banner knowledge pool

24 June 2021

ESTREL APP

31 May 2021

ECRIN Certificate

15 March 2021

MDR

3 May 2021, update 26 May 2021

Graphic study registration

10 March 2021

Since the introduction of mandatory registration, the rate of reported prospective studies and the quality of study information has been steadily increasing.

The new figures on clinical research activity at the University Hospital Basel.

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