Research Focus

Cardiovascular & Perioperative Medicine

Area of Research

Perioperative outcome research

• 07/2022 – present  
  CIBOSurg - ClassIntra^® for Better Outcomes in Surgery
  Federal Quality Commission (main applicant grant CHF 45,000)
  Foundation for Research and Education in Anaesthesia (main applicant grant CHF 174,000)
• 05/2019 – present  
  EEG - more than only a BIS index
  Foundation for Research and Education University Basel (main applicant grant CHF 25,000)
  Foundation for Research and Education in Anaesthesia (main applicant grant CHF 87,100)
  Jubiläumsstiftung SwissLife (main applicant C. Burkhart CHF 10,000)
• 01/2018- 01/2023   
  Discrepancy in reporting of perioperative complications
  Foundation for Research and Education University Basel (co-applicant grant CHF 16,000)
  Foundation for Research and Education in Anaesthesia (main applicant grant CHF 2,900)
• 04/2015 - 06/2020  
  Prospective validation validation of ClassIntra^® - international, multicentre cohort study
  University of Basel research fund for outstanding junior researcher (main applicant CHF 78,888)
  Two additional grants as main and co-applicant (CHF 44,500)
• 02/2015 - 08/2019  
  Generalisability of randomised trials of the PIEB technique used for maintenance of labour analgesia:
  a prospective cohort study(main applicant grant CHF 11,700)
• 01/2014 - 01/2017  
  Carbetocin trial (main applicant for 3 grants, total CHF 70,000 und GBP 5,000)

National Collaborations

CIBOSurg - ClassIntra® for better outcomes in surgery

• Prof. Dr. med. Pierre-Alain Clavien, University Zurich
• Prof. Dr. med. Milo Puhan, Director Epidemiology, Biostatistics and Public Health Institute, University of Zurich
• Prof. Dr. med. Dieter Hahnloser, Department of Surgery, University Hospital Lausanne
• PD Dr. med. Bastian Grande, Department of Anaesthesiology, University Hospital Zurich
• Prof. Dr. med. Valentin Neuhaus, Traumatology, University Hospital Zurich
• PD Dr. med. Andreas Vogt, Department of Anaesthesiology, University Hospital Berne
• Dr. med. Christoph Burkhart, Cantonal Hospital Graubünden
• Prof. Dr. med. Jürg Metzger, LUKS
• Dr. med. Nicola Ledingham, EOC Lugano
• Prof. Dr. Lauren Clack, Institute of Implementation Science in Healthcare, University of Zurich

Multicentre RCT: EEG - more than only a BIS index

• PD Dr. med. Andrea Kopp Lugli, Cantonal Hospital Baden
• med. pract. Simon Funk (doctoral candidate)
• Dr. med. Martin Lohri, USB

Importance of multimorbidity in perioperative risk assessment - multicentre, international cohort study

• Prof. Dr. med. Dieter Hahnloser, Department of Surgery, University Hospital Lausanne
• Dr. med. Heinz Bruppacher, Department of Anaesthesiology, Schulthess Clinique Zurich
• Prof. Dr. med. Thomas Erb, Head of Department of Anaesthesiology, University Children's Hospital Basel
• Dr. med. Philippe Schumacher, Department of Anaesthesiology and Intensive Care Medicine, Bürgerspital Solothurn
• Prof. Dr. med. Harry van Goor, PhD, Department of Surgery, Radboud university medical centre, Nijmegen, the Netherlands
• Prof. Dr. med. Ben Loveday, PhD, Department of Surgery, University of Auckland, New Zealand

Multicentre RCT: EEG - more than only a BIS index

• Dr. med. Anita Lüthy, Cantonal Hospital Aarau
• Dr. med. Martin Lohri, USB
• Dr. med. Christoph Burkhart, Cantonal Hospital Graubünden
• Dr. med. Lien Jakus, HUG
• Dr. med. Julien Maillard, HUG

International Collaborations

    ClassIntra® validation study and follow-up projects (selection)

• Prof. Dr. med. Harry van Goor, PhD, Department of Surgery, Radboud university medical centre, Nijmegen, the Netherlands
• Prof. Dr. med. Ben Loveday, PhD, Department of Surgery, University of Auckland, New Zealand
• Prof. Dr. med. Alexander Engel, Department of Surgery, University of Sydney, Royal North Shore Hospital, Sydney, Australia

• Multicentre RCT: Titration of propofol (Doctoral thesis Simon Funk)
• CIBOSurg - ClassIntra^® for better outcomes in surgery. Current progress: waiting for ethical approval, grant applications, start context analysis
• Epidemiology of multimorbidity in the perioperative patient population and its effect on perioperative outcomes - international, multicentre study (Doctoral thesis Luzius Angehrn and Christian Grob). Current progress: manuscript under review in Anesthesiology
• Multicentre RCT: EEG in general anaesthesia - more than only a BIS index. Current progress: study protocol published in BMJ Open (Doctoral thesis Bettina Gruber), recruitment finalised, drafting manuscript of main paper
• Detailed evaluation of all intraoperative adverse events: Secondary analysis of the prospective validation study of ClassIntra® (PhD thesis Larsa Gawria). Current progress: revised version of manuscript submitted to Journal of Clinical Medicine