Critical Care & Respiratory Medicine

Research in this area focuses on asthma and COPD in adults and on asthma and lung development in infants and children. In emergency medicine, the focus is on the influence of doctor-patient communication and human factors on patient outcome.

Selected current publications

Violence against healthcare professionals in intensive care units: a systematic review and meta-analysis of frequency, risk factors, interventions, and preventive measures. Berger S, Grzonka P, Frei AI, Hunziker S, Baumann SM, Amacher SA, Gebhard CE, Sutter R. Crit Care. 2024 Feb 26;28(1):61. doi: 10.1186/s13054-024-04844-z. PMID: 38409034; PMCID: PMC10898135.

Sex-related differences in adult patients with status epilepticus: a seven-year two-center observation; Baumann SM, De Stefano P, Kliem PSC, Grzonka P, Gebhard CE, Sarbu OE, De Marchis GMHunziker S, Rüegg S, Kleinschmidt A, Pugin J, Quintard H, Marsch S, Seeck M, Sutter R.; Crit Care. 2023 Aug 5;27(1):308. doi: 10.1186/s13054-023-04592-6. PMID: 37543625; PMCID: PMC10403848

Airway smooth muscle area to predict steroid responsiveness in COPD patients receiving triple therapy (HISTORIC): a randomised, placebo-controlled, double-blind, investigator-initiated trial. Stolz D, Papakonstantinou E, Pascarella M, Jahn K, Siebeneichler A, Darie AΜ, Herrmann MJ, Strobel W, Salina A, Grize L, Prince SS, Tamm M. Eur Respir J. 2023 Jun 29:2300218. doi: 10.1183/13993003.00218-2023. Epub ahead of print. PMID: 37385657.

Subjective and objective survival prediction in mechanically ventilated critically ill patients: a prospective cohort study  Boeck L, Pargger H, Schellongowski P, Luyt CE, Maggiorini M, Jahn K, Muller G, Lötscher R, Bucher E, Cueni N, Staudinger T, Chastre J, Siegemund M, Tamm M, Stolz DCritical Care. 2023 Apr 19;27(1):150.

Temporal trends in mortality and provision of intensive care in younger women and men with acute myocardial infarction or stroke. Arslani K, Tontsch J, Todorov A, Gysi B, Kaufmann M, Kaufmann F, Hollinger A, Wildi K, Merdji H, Helms J, Siegemund M, Gebhard C, Gebhard CE; Swiss Society of Intensive Care Medicine. Crit Care. 2023 Jan 12;27(1):14. doi: 10.1186/s13054-022-04299-0. PMID: 36635740; PMCID: PMC9835383.

Predicting neurological outcome in adult patients with cardiac arrest: systematic review and meta-analysis of prediction model performance. Amacher SA, Blatter R, Briel M, Appenzeller-Herzog C, Bohren C, Becker C, Beck K, Gross S, Tisljar K, Sutter R, Marsch S, Hunziker S. Crit Care. 2022 Dec 11;26(1):382. doi: 10.1186/s13054-022-04263-y. PMID: 36503620; PMCID: PMC9741710.

Towards the elimination of chronic obstructive pulmonary disease: a Lancet Commission. Stolz D, Mkorombindo T, Schumann DM, Agusti A, Ash SY, Bafadhel M, Bai C, Chalmers JD, Criner GJ, Dharmage SC, Franssen FME, Frey U, Han M, Hansel NN, Hawkins NM, Kalhan R, Konigshoff M, Ko FW, Parekh TM, Powell P, Rutten-van Mölken M, Simpson J, Sin DD, Song Y, Suki B, Troosters T, Washko GR, Welte T, Dransfield MT. Lancet. 2022 Sep 5:S0140-6736(22)01273-9. Epub ahead of print.

Comparison of different clinical risk scores to predict long-term survival and neurological outcome in adults after cardiac arrest: results from a prospective cohort study. Blatter R, Amacher SA, Bohren C, Becker C, Beck K, Gross S, Tisljar K, Sutter R, Marsch S, Hunziker S. Ann Intensive Care. 2022 Aug 17;12(1):77. doi: 10.1186/s13613-022-01048-y. PMID: 35978065; PMCID: PMC9385915.

Fast multiplex bacterial PCR of bronchoalveolar lavage for antibiotic stewardship in hospitalised patients with pneumonia at risk of Gram-negative bacterial infection (Flagship II): a multicentre, randomised controlled trial. Darie AM, Khanna N, Jahn K, Osthoff MBassetti S, Osthoff M, Schumann DM, Albrich WC, Hirsch H, Brutsche M, Grize L, Tamm M, Stolz DLancet Respir Med. 2022 May 23:S2213-2600(22)00086-8. Epub ahead of print. 

Long-term Survival After Out-of-Hospital Cardiac Arrest: A Systematic Review and Meta-analysis. Amacher SA, Bohren C, Blatter R, Becker C, Beck K, Mueller J, Loretz N, Gross S, Tisljar K, Sutter R, Appenzeller-Herzog C, Marsch SHunziker SJAMA Cardiol. 2022 May 4. Online ahead of print.

Increased Impact of Air Pollution on Lung Function in Preterm versus Term Infants: The BILD Study. Decrue F, Gorlanova O, Salem Y, Vienneau D, de Hoogh K, Gisler A, Usemann J, Korten I, Nahum U, Sinues P, Schulzke S, Fuchs O, Latzin P, Röösli M, Frey U; BILD study group. Am J Respir Crit Care Med. 2022 Jan 1;205(1):99-107. doi: 10.1164/rccm.202102-0272OC. PMID: 34587471.

Gender-focused training improves leadership of female medical students: A randomised trial. Hochstrasser SR, Amacher SA, Tschan F, Semmer NK, Becker C, Metzger K, Hunziker S, Marsch S. Med Educ. 2021 Sep 2. doi: 10.1111/medu.14658. Epub ahead of print. PMID: 34473373.

Effect of Bedside Compared With Outside the Room Patient Case Presentation on Patients' Knowledge About Their Medical Care : A Randomized, Controlled, Multicenter Trial. Becker C, Gamp M, Schuetz P, Beck K, Vincent A, Hochstrasser S, Metzger K, Widmer M, Thommen E, Mueller B, Fux CA, Leuppi JD, Schaefert R, Langewitz W, Trendelenburg M, Breidthardt T, Eckstein J, Osthoff M, Bassetti S, Hunziker S. Ann Intern Med. 2021 Jun 29. doi: 10.7326/M21-0909. Epub ahead of print. PMID: 34181449.

Maternal asthma is associated with reduced lung function in male infants in a combined analysis of the BLT and BILD cohorts. de Gouveia Belinelo P, Collison AM, Murphy VE, Robinson PD, Jesson K, Hardaker K, de Queiroz Andrade E, Oldmeadow C, Martins Costa Gomes G, Sly PD, Usemann J, Appenzeller R, Gorlanova O, Fuchs O, Latzin P, Gibson PG, Frey U, Mattes J. Thorax. 2021 Feb 25:thoraxjnl-2020-215526. doi: 10.1136/thoraxjnl-2020-215526. Epub ahead of print. PMID: 33632766.

Serum Neurofilament Light Chain Levels in the Intensive Care Unit: Comparison between Severely Ill Patients with and without Coronavirus Disease 2019. Sutter R, Hert L, De Marchis GM, Twerenbold R, Kappos L, Naegelin Y, Kuster GM, Benkert P, Jost J, Maceski AM, Rüegg S, Siegemund M, Leppert D, Tschudin-Sutter S, Kuhle J.  Ann Neurol. 2020 Dec 30. doi: 10.1002/ana.26004. Epub ahead of print. PMID: 33377539.

Association of Communication Interventions to Discuss Code Status With Patient Decisions for Do-Not-Resuscitate Orders: A Systematic Review and Meta-analysis.Becker C, Lecheler L, Hochstrasser S, Metzger KA, Widmer M, Thommen EB, Nienhaus K, Ewald H, Meier CA, Rueter F, Schaefert R, Bassetti S, Hunziker S. JAMA Network Open. 2019 Jun 5;2(6):e195033. doi: 10.1001/jamanetworkopen.2019.5033.