Prof. Mirjam
Christ-Crain, MD
Position(s)
Deputy Chief Physician Endocrinology
Co-Head Department of Clinical Research
Institution
University Hospital Basel
Phone +41 61 328 70 80
Research Group Mirjam Christ-Crain
Research Focus
Endocrinology, Metabolism & Developmental Disorders
Area of Research
Water and electrolyte disorders, in particular diagnosis and therapy in polyuria and polydipsia syndrome and hyponatremia.
Corticosteroids and other stress hormones for outcome prediction of various diseases and as immunomodulatory treatment.
Approved Research Projects
CARGOx study (Copeptin after arginine infusion compared to copeptin after hypertonic saline infusion for the differential diagnosis of diabetes insipidus)
SANDx study (SGLT-2 inhibitors for treatment of SIADH, a placebo-controlled randomised study)
Glucacop (Glucagon for the differential diagnosis of Diabetes insipidus, a randomized placebo-controlled trial)
FERTIL (IL-1 antagonism for patients with PCOS)
Collaborations
National Collaborations
- Prof. Beat Müller and Prof. Philipp Schütz, Kantonsspital Aarau
- Prof. Christoph Henzen, Kantonsspital Luzern
- PD. Dr. Stefan Bilz, Kantonsspital St.Gallen
- Prof. Felix Beuschlein, Universitätsspital Zürich
- Prof. Nelly Pitteloud, Universitätsspital Lausanne (CHUV)
International Collaborations
- Prof. Willem Jan Bos, Nieuwegein Hospital (the Netherlands)
- Prof. Martin Fassnacht, Universitätsspital Würzburg
- PD Dr. Wiebke Fenske, Universitätsspital Leipzig
- Prof. Antonio Ribeiro Jr., Belo Horizonte, Brazil
- Prof. Ewout Hoorn, Rotterdam University Hospital
- Prof. Volker Burst, Uniklinik Köln
- Prof. Alessandro Peri, Florence
- Prof. Mark Sherlock and Prof. Chris Thompson, Beaumont Hospital Dublin
- Prof. Darko Kastelan, University Hospital Centre Zagreb,Croatia
Ongoing Research Projects
GOLD study (Effects of GLP-1 analogues on fluid intake in patients with primary polydipsia): randomized placebo-controlled cross-over study evaluating the effect of GLP-1 analogs on fluid intake in patients with primary polydipsia
HIT study (Hyponatremia Intervention study)
COMEN study (Copeptin in monosymptomatic enuresis nocturna): observational study evaluating copeptin as a predictor for treatment response in children with monosymptomatic enuresis nocturna.
EMPOWER (SGLT-2 Inhibitoren bei eu-und hypervolämer Hyponatriämie, a randomized placebo-controlled trial)
OxyMa (MDMA to stimulate oxytocin levels in diabetes insipidus, a randomized placebo-controlled trial)
Research Team
Cemile Bathelt
Leading Study Nurse
DAS Clinical Trial Practice and Management
Phone +41 61 556 53 04
Dr. med. Julie Refardt
Co-leader of research group
Senior Physician
Phone +41 61 328 76 08
Joyce Santos de Jesus
Senior Study Nurse, DAS Clinical Trial Practice and Management
Phone +41 61 328 50 91