Research Focus

Endocrinology, Metabolism & Developmental Disorders

Area of Research

Outcome-oriented health services research in the case of acute-hospitalised, polymorbid medical patients: risk-stratified diagnostics, therapy and allocation of limited hospital resources by interdisciplinary, interprofessional, occupational and cross-institutional approaches, also with the help of biomarker

• Müller B., Albrich W.A., de Geest S. Calcitonin Gene derived peptides for an Optimized Patient Transfer using an Innovative Multidisciplinary Assessment in the Canton Aargau (OPTIMA II) 32003B_135222. Competitive Research Grant (“Freies Forschungsgesuch”) Apr 2011 – Mar 2014
• Müller B., Kutz A., Schuetz P., de Geest S. Integrative Hospital Treatment in Older patients to benchmark and improve Outcome and Length of stay - the In-HospiTOOL study 407440_167376. Competitive Research Grant National Research Program (NRP) 74 (“Smarter Health Care”) Jan 2016 – Dec 2020
• Hugo und Elsa Isner Stiftung Müller B., Kutz A., Schuetz P., de Geest S. Integrative Hospital Treatment in Older patients to benchmark and improve Outcome and Length of stay - the In-HospiTOOL study 407440_167376. Jan 2016 – Dec 2017 (CHF 205`273) Jan 2018 – Dec 2019
• A., Schuetz P., de Geest S. Integrative Hospital Treatment in Older patients to benchmark and improve Outcome and Length of stay - the In-HospiTOOL study 407440_167376. Forschungsrat Kantonsspital Aarau Jan 2016 – Dec 2020
• Müller B., Kutz A., Schuetz P., de Geest S. Integrative Hospital Treatment in Older patients to benchmark and improve Outcome and Length of stay - the In-HospiTOOL study 407440_167376. W&W Fonds, Kantonsspital Aarau AG Jan 2016 – Dec 2020
• Principal Mentor for Prof. Philipp Schuetz, M.D. SNF Professorship 2014-2018. The EFFORT-Project. Effect of Early Nutritional Therapy on Frailty, Functional Outcomes and Recovery of Undernourished Medical Inpatients Trial

National Collaborations
- Numerous: University, Cantonal and Regional Hospitals
- Universities Basel, Berne, Zürich

International Collaborations
- Numerous

• Blum C.A., Schuetz P., Nigro N., Winzeler B., Arici B., Refardt J., Urwyler S.A., Rodondi N., Blum M.R., Briel M., Mueller B., Christ-Crain M. Adrenal function testing does not predict corticosteroid responsiveness in community-acquired pneumonia. (submitted)
• Struja T., Mundwiler E., Eckart A., Kutz A., Huber A., Kraenzlin M., Mueller B., Meier C., Bernasconi L. Schuetz P. Metabolomic markers for prediction of relapse in Graves’ disease: results of an observational pilot study. (submitted)
• Zurfluh S., Nickler M., Ottiger M., Steuer C., Kutz A., Christ-Crain M., Zimmerli W., Thomann R., Hoess C., Henzen C., Bernasconi L., Huber A., Mueller B., Schuetz P., for the ProHOSP study group. Dihydrotestosterone is a predictor for mortality in males with CAP: Results of a 6-year follow-up study. (submitted)
• Eckart A., Struja T., Kutz A., Baumgartner A., Baumgartner T., Zurfluh S., Neeser O., Huber A., Mueller B., Schuetz P. The interplay of nutritional status, inflammation, and serum albumin levels during acute illness: results of a prospective cohort study. (submitted)
• Sailer C.O., Winzeler B., Nigro N., Bernasconi L., Mueller B., Christ-Crain M. Influence of outdoor temperature on incidence and etiology of hyponatremia (submitted)
• Zweifel C., Katan M., Jost G., Schuetz P., Morgenthaler N.G., Siegemund M., Wasner M., Merlo A., Mueller B., Christ-Crain M. Copeptin for diagnosis of diabetes insipidus in patients undergoing brain tumor surgery: a case series. (submitted)
• Spaniol P.M., Marincek M., Gloy V., Krause M., Mueller-Brand J., Stettler C., Trepp R. Christ E.R., Bally M., Blum C., Kreutle V., Borm K., Jüni P., Briel M., Mueller B., Walter M.W. The Safety Profile of Radioiodine in the treatment of differentiated thyroid cancer or hyperthyroidism (SPRINT): Systematic Review and Meta-Analysis. (ongoing)