Research Focus

Immunology & Infectious Diseases

Area of Research

Genetics and pathophysiology of inflammatory skin diseases, especially neutrophilic dermatoses; Image-based classification of dermatoses using machine learning

Investigator-initiated trials:
• IRASPEN Registry
• APRESCALP Study
• SDNTT Registry
• MELVEC Study
• Computer-based Skin Aging Simulation for Skin Cancer Prevention
• AcneDect Study
• Skin biopsies and blood for epigenetics
• Cutaneous surgery disfigurement trial
• Skinobi: Skin moisture and pigmentation levels
• The Color of Itch; Itch Modification by Color Viewing

Industry-sponsored trials:
• POSITIVE
• MEASURE-UP1
• VALUE Registry
• Serena Registry
• BI 1368-0016: moderate to severe Palmoplantar Pustulosis (PPP)
• BI 1368-0013: Generalized Pustular Psoriasis (GPP)

National Collaborations

Swiss Dermatology Network for Targeted Therapies (PI Navarini)

International Collaborations

International Rare and Severe Psoriasis Expert Network (PI Navarini)

Investigator-initiated trials:

• International Rare And Severe Psoriasis Expert Network (IRASPEN) Study: NCT04359394
• Apremilast Treatment for Pruritus and Quality of Life in Scalp Psoriasis (APRESCALP): NCT03553433
• Swiss Dermatology Network of Targeted Therapies (SDNTT) Registry: NCT01706692
• Acne Detection Software (AcneDect) (AcneDect) NCT04060160
• Clinical performance of the new artificial intelligence-powered 3D total body photography system VECTRA® in early melanoma detection and its impact on patients’ burden of disease: A prospective cohort study in a real-world setting (Short title: Melanoma Detection in Switzerland With VECTRA (Acronym: MELVEC)): NCT04605822
• A prospective observational multicenter study to evaluate the performance and patient acceptance of the ATBM master device for automated total body mapping (Acronym: ATBM-MASTER international study): NCT04605822
• Total body dermoscopic evaluation of pregnancy-related changes in melanocytic nevi using the FotoFinder ATBM master system and the impact of artificial intelligence assisted examinations on the patients’ skin cancer screening experience: A prospective two-arm controlled observational study. (Acronym: PREM = Pregnancy-related changes in melanocytic nevi) (EKNZ: 2020-02494)
• Computer-based Skin Aging Simulation for Skin Cancer Prevention: NCT04532437
• Acceptance of teledermatology compared to face-to-face consultation from the providers’ and users’ perspectives: NCT04495036
• German-speaking Melanoma Patients willingness to tolerate toxicity during adjuvant treatment (GERMELATOX-A)
• Skin biopsies and blood for epigenetics
• Skinobi: Skin moisture and pigmentation levels
• Patient Reported Outcome Measures After Treatment of Skin Cancers on the Face: NCT04485442 (gemeinsames Projekt mit Plastischer Chirurgie)

Industry-sponsored trials:

• POSITIVE
• MEASURE-UP1
• VALUE