This research focus covers a broad spectrum. It ranges from studies of pathophysiological processes of multidrug-resistant bacteria, to the optimisation of therapies for avariety of inflammatory diseases, to research into the causes and effects of vaccination scepticism.

• Autoimmune diseases
• Environmental factors
• Experimental Rheumatology
• Giant cell arteritis
• Hirschsprung's disease
• HIV therapies
• Inflammatory skin diseases
• Kidney transplantation
• Liver Cirrhosis
• Mastocytosis, urticaria and atopic dermatitis
• Metabolic and aging-associated complications of HIV infection
• Optimization of antibiotic therapy in hospitals
• Research in primary care setting
• Role of mitochondrial DNA in inflammation
• T-cell responses in viral infections and autoimmune disease
• Transmission of multidrug-resistant bacteria in the hospital
• Transplant immunology
• Tuberculosis in children
• Vaccination scepticism
• Viral and fungal infections, especially in immunocompromised patients
• Viral infections
• Viruses and bacteria

Swissped RECOVERY Trial Group. Methylprednisolone versus intravenous immunoglobulins in children with paediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2 (PIMS-TS): an open-label, multicentre, randomised trial. Welzel T, Atkinson A, Schöbi N, Andre MC, Bailey DGN, Blanchard-Rohner G, Buettcher M, Grazioli S, Koehler H, Perez MH, Trück J, Vanoni F, Zimmermann P, Sanchez C, Bielicki JA, Schlapbach LJ;  Lancet Child Adolesc Health. 2023 Feb 3:S2352-4642(23)00020-2. doi: 10.1016/S2352-4642(23)00020-2. Epub ahead of print. PMID: 36746174; PMCID: PMC9897729.

Effect of Antibiotic Prescription Audit and Feedback on Antibiotic Prescribing in Primary Care: A Randomized Clinical Trial. Aghlmandi S, Halbeisen FS, Saccilotto R, Godet P, Signorell A, Sigrist S, Glinz D, Moffa G, Zeller A, Widmer AF, Kronenberg A, Bielicki J, Bucher HC. JAMA Intern Med. 2023 Feb 6. doi: 10.1001/jamainternmed.2022.6529. Epub ahead of print. PMID: 36745412.

Impact of nucleic acid extraction procedures on human papillomavirus (HPV) detection and genotyping. Naegele K, Weissbach FH, Leuzinger K, Gosert R, Bubendorf L, Hirsch HH. J Med Virol. 2023 Feb;95(2):e28583. doi: 10.1002/jmv.28583. PMID: 36794677.

Leukocyte Count and Coronary Artery Disease Events in People with HIV: A Longitudinal Study. Avery EF, Kleynhans JN, Ledergerber B, Schoepf IC, Thorball CW, Kootstra NA, Reiss P, Ryom L, Braun DL, Thurnheer MC, Marzolini C, Seneghini M, Bernasconi E, Cavassini M, Buvelot H, Kouyos RD, Fellay J, Günthard HF, Tarr PE; Swiss HIV Cohort Study. Clin Infect Dis. 2023 Jan 23:ciad033. doi: 10.1093/cid/ciad033. Epub ahead of print. PMID: 36688465.

How can patients with Clostridioides difficile infection on concomitant antibiotic treatment be best managed? Fitzpatrick F, Safdar N, van Prehn J, Tschudin-Sutter S. Lancet Infect Dis. 2022 Nov;22(11):e336-e340. doi: 10.1016/S1473-3099(22)00274-2. Epub 2022 May 23. PMID: 35617982.

Cumulative Antibiotic Exposure in the First 5 Years of Life: Estimates for 45 Low- and Middle-Income Countries From Demographic and Health Survey Data. Levine GA, Bielicki J, Fink G. Clin Infect Dis. 2022 Oct 29;75(9):1537-1547. doi: 10.1093/cid/ciac225. PMID: 35325088.

Exacerbation of familial intrahepatic cholestasis in conjunction with COVID-19 vaccination. Guri Y, Vosbeck J, Dickenmann M, Jetter A, Bernsmeier C. J Hepatol. 2022 Sep;77(3):872-874. Epub 2022 May 16.

Polygenic Risk Scores for Prediction of Subclinical Coronary Artery Disease in Persons Living with HIV: The Swiss HIV Cohort Study Schoepf IC, Thorball CW, Kovari H, Ledergerber B, Buechel RR, Calmy A, Weber R, Kaufmann PA, Nkoulou R, Schwenke JM, Braun DL, Fellay J, Tarr PE; Swiss HIV Cohort Study. Clin Infect Dis. 2022 Sep 13:ciac758.  Epub ahead of print.

IL-20 subfamily cytokines impair the oesophageal epithelial barrier by diminishing filaggrin in eosinophilic oesophagitis. Kaymak T, Kaya B, Wuggenig P, Nuciforo S, Göldi A; Swiss EoE Cohort Study Group (SEECS), Oswald F, Roux J, Noti M, Melhem H, Hruz P, Niess JH. Gut. 2022 May 25:gutjnl-2022-327166. Epub ahead of print.

How can patients with Clostridioides difficile infection on concomitant antibiotic treatment be best managed? Fitzpatrick F, Safdar N, van Prehn J, Tschudin-Sutter S. Lancet Infect Dis. 2022 May 23:S1473-3099(22)00274-2. Epub ahead of print.

Fast multiplex bacterial PCR of bronchoalveolar lavage for antibiotic stewardship in hospitalised patients with pneumonia at risk of Gram-negative bacterial infection (Flagship II): a multicentre, randomised controlled trial. Darie AM, Khanna N, Jahn K, Osthoff M, Bassetti S, Osthoff M, Schumann DM, Albrich WC, Hirsch H, Brutsche M, Grize L, Tamm M, Stolz D. Lancet Respir Med. 2022 May 23:S2213-2600(22)00086-8. Epub ahead of print. 

Skeletal Muscle Disorders: A Non-cardiac Source of Cardiac Troponin T. du Fay de Lavallaz J, Prepoudis A, Wendebourg MJ, Kesenheimer E, Kyburz D, Daikeler T, Haaf P, Wanschitz J, Löscher WN, Schreiner B, Katan M, Jung HH, Maurer B, Hammerer-Lercher A, Mayr A, Gualandro DM, Acket A, Puelacher C, Boeddinghaus J, Nestelberger T, Lopez-Ayala P, Glarner N, Shrestha S, Manka R, Gawinecka J, Piscuoglio S, Gallon J, Wiedemann S, Sinnreich M, Mueller C; BASEL XII Investigators. Circulation. 2022 Apr 7. doi: 10.1161/CIRCULATIONAHA.121.058489. Epub ahead of print. PMID: 35389756.

Coronary Artery Disease-Associated and Longevity-Associated Polygenic Risk Scores for Prediction of Coronary Artery Disease Events in Persons Living With Human Immunodeficiency Virus: The Swiss HIV Cohort Study Schoepf IC, Thorball CW, Ledergerber B, Engel T, Raffenberg M, Kootstra NA, Reiss P, Hasse B, Marzolini C, Thurnheer C, Seneghini M, Bernasconi E, Cavassini M, Buvelot H, Kouyos R, Günthard HF, Fellay J, Tarr PE; Swiss HIV Cohort Study. Clin Infect Dis. 2021 Nov 2;73(9):1597-1604.

Identification of a Cluster of Extended-spectrum Beta-Lactamase-Producing Klebsiella pneumoniae Sequence Type 101 Isolated From Food and Humans. Aguilar-Bultet L, Bagutti C, Egli A, Alt M, Maurer Pekerman L, Schindler R, Furger R, Eichenberger L, Roloff T, Steffen I, Huebner P, Stadler T, Tschudin-Sutter S. Clin Infect Dis. 2021 Jul 15;73(2):332-335. doi: 10.1093/cid/ciaa1164. PMID: 32776135; PMCID: PMC8282321.

Effect of Bedside Compared With Outside the Room Patient Case Presentation on Patients' Knowledge About Their Medical Care : A Randomized, Controlled, Multicenter Trial Becker C, Gamp M, Schuetz P, Beck K, Vincent A, Hochstrasser S, Metzger K, Widmer M, Thommen E, Mueller B, Fux CA, Leuppi JD, Schaefert R, Langewitz W, Trendelenburg M, Breidthardt T, Eckstein J, Osthoff M, Bassetti S, Hunziker S. Ann Intern Med. 2021 Jun 29. doi: 10.7326/M21-0909. Epub ahead of print. PMID: 34181449.

SARS-CoV-2 outbreak in a tri-national urban area is dominated by a B.1 lineage variant linked to a mass gathering event. Stange M, Mari A, Roloff T, Seth-Smith HM, Schweitzer M, Brunner M, Leuzinger K, Søgaard KK, Gensch A, Tschudin-Sutter S, Fuchs S, Bielicki J, Pargger H, Siegemund M, Nickel CH, Bingisser R, Osthoff M, Bassetti S, Schneider-Sliwa R, Battegay M, Hirsch HH, Egli A. PLoS Pathog. 2021 Mar 19;17(3):e1009374. doi: 10.1371/journal.ppat.1009374. Epub ahead of print. PMID: 33740028.

Evaluating antimicrobial effectiveness in environmental microbiology. Widmer AF, Frei R. Clin Infect Dis. 2021 Jan 10:ciab013. doi: 10.1093/cid/ciab013. Online ahead of print.

SARS-CoV-2 phylogeny during the early outbreak in the Basel area, Switzerland: import and spread dominated by a single B.1 lineage variant (C15324T) Madlen Stange, Alfredo Mari, Tim Roloff, Helena M. B. Seth-Smith, Michael Schweitzer, Myrta Brunner, Karoline Leuzinger, Kirstine K. Søgaard, Alexander Gensch, Sarah Tschudin-Sutter, Simon Fuchs, Julia Anna Bielicki, Hans Pargger, Martin Siegemund, Christian H. Nickel, Roland Bingisser, Michael Osthoff, Stefano Bassetti, Rita Schneider-Sliwa, Manuel Battegay, Hans H. Hirsch, Adrian Egli medRxiv 2020.09.01.20186155; doi: doi.org/10.1101/2020.09.01.20186155

SARS-CoV-2 PCR testing of skin for COVID-19 diagnostics: a case report. Jamiolkowski D, Mühleisen B, Müller S, Navarini AA, Tzankov A, Roider E. Lancet. 2020 Aug 29;396(10251):598-599. doi: 10.1016/S0140-6736(20)31754-2. Epub 2020 Aug 13. PMID: 32798450

Dose-dependent effectiveness of acellular pertussis vaccine in infants: A population-based case-control study. Mack I, Erlanger TE, Lang P, Sinniger P, Perisa D, Heininger U. Vaccine. 2020 Feb 5;38(6):1444-1449. doi: 10.1016/j.vaccine.2019.11.069. Epub 2019 Dec 5.

Emergency management of status epilepticus in a high-fidelity simulation: A prospective study. Sutter R, Tisljar K, Opić P, De Marchis GM, Bassetti S, Bingisser R, Hunziker S, Marsch S. Neurology. 2019 Oct 8. pii: 10.1212/WNL.0000000000008461. doi: 10.1212/WNL.0000000000008461. [Epub ahead of print]