Research | Department of Clinical Research

Academic clinical research

Research at our department is focused on unmet medical and patient-oriented needs. They arise from clinical practice and encompass almost all medical disciplines.

[Translate to English:] BRACE-AFib-Studie

Investigator-initiated Clinical Trial (IICT)

BRACE-AFib study

Beta-blocker Replacement And Calcium channel blockers Evaluation in Atrial Fibrillation

Investigator-Initiated Clinical trial (IICT)

NoDoubt study

Efficacy of non-opioid drugs in addition to opioid therapy for cancer pain management: a double-blind, randomized, three arm, placebo-controlled trial assessing the key non-opioids dipyrone (metamizole) and ibuprofen: NoDoubt-trial

Cohort/Register

SWISS-CASCADE

Swiss Cancer Genetic Predisposition Cascade Screening

Research groups at the DKF

Publications

Investigator-initiated clinical trial (IICT)

DISTAL study

Endovascular therapy plus best medical treatment (BMT) versus BMT alone for medium vessel occlusion stroke - a pragmatic, international, multicentre, randomized trial

Investigator-initiated clinical trial (IICT)

dreaMS_V2

Development of Digital Biomarkers in Multiple Sclerosis (Validation Study 2)

Investigator-initiated clinical trial (IICT)

EMINENT-ICH study

Early minimally invasive image-guided endoscopic evacuation of intracerebral haemorrhage: a randomized controlled trial

Investigator-initiated clinical trial (IICT)

ESTREL study

Enhancement of stroke rehabilitation with Levodopa: A randomized controlled trial

Investigator-initiated clinical trial (IICT)

ICARUS study

Intracranial atherosclerosis related large-vessel occlusion treated with urgent stenting - a pragmatic, international, multicentre, randomized trial

Investigator-initiated clinical trial (IICT)

KIDS-STEP study

Betamethasone Therapy in Hospitalized Children with Community-aquired Pneumonia (CAP)

Investigator-initiated clinical trial (IICT)

LIPS study

Combination antibiotic treatment with linezolid for Staphylococcus aureus bacteraemia: a randomized controlled trial

Investigator-Initiated Clinical Trial (IICT)

LYMPH study

Surgical versus conservative complex physical decongestion Therapy (CDT) for chronic breast cancer-related lymphedema (BCRL): A pragmatic, randomized, multicenter superiority trial

INVESTIGATOR-INITIATED CLINICAL TRIAL (IICT)

MATAO study

Aromatase inhibitors for patients with epithelial ovarian cancer

Investigator-Initiated Clinical Trial

MultiSCRIPT study

Personalized medicine in multiple sclerosis a pragmatic platform trial embedded within SMSC

Data research

NCCR AntiResist

National Centre of Competence in Research "New approaches to combat antibiotic-resistant bacteria"

Cohort/Registry

NOACISP

New Oral Anticoagulants in Stroke Patients

Investigator-initiated clinical trial (IICT)

OxyTUTION study

Oxytocin substitution therapy in patients with central diabetes insipidus: a double-blind randomized-controlled trial

Investigator-initiated clinical trial (IICT)

PFOA II study

Treatment of patellofemoral osteoarthritis with nasal chondrocyte-based engineered cartilage (N-TEC) implantation in a randomized, controlled, multi-center phase II clinical trial

Investigator-initiated clinical trial (IICT)

PREPEC study

Pre- versus sub-pectoral implant-based breast reconstruction after skin- and nipple-sparing mastectomy: A pragmatic, multicenter, randomized, superiority trial

Investigator-initiated clinical trial (IICT)

RELIEF study

Restricted versus liberal fluid intake for prevention of bronchopulmonary dysplasia - a cluster-randomized multiple period cross-over trial

Cohort/Registry

SOL-DHR

Swiss Organ Living-Donor Health Registry

Cohort/Registry

SwissAF

Swiss Atrial Fibrillation Cohort

Cohort/Registry

SMSC

Swiss Multiple Sclerosis Cohort

Cohort/Registry

SSR

Swiss Stroke Registry

Cohort/Registry

STCS

Swiss Transplant Cohort Study

Investigator-initiated clinical trial (IICT)

TAXIS study

Tailored axillary surgery with or without axillary lymph node dissection followed by radiotherapy in patients with clinically node-positive breast cancer

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Academic clinical research

Investigator-initiated Clinical Trial (IICT)

BRACE-AFib study

Investigator-Initiated Clinical trial (IICT)

NoDoubt study

Cohort/Register

SWISS-CASCADE

Research groups at the DKF