Dirk Fischer

Prof. Dr. med.
Dirk Fischer

Position(s)
Senior Physician Neuro- and Developmental Pediatrics, Senior Physician Electrophysiology

Institution
University Children's Hospital Basel

Phone
+41 61 704 12 12

Email

Research Group Dirk Fischer

 

Research Focus

Neurology

Area of Research

Hereditary muscle diseases, specifically research of objective imaging techniques for assessing the musculature


Approved Research Projects

  • Pilot trial of metformin and L-arginine in DMD (NCT02516085)
  • Pilot trial of metformin and L-citrulline in BMD (NCT02018731)
  • Double blind placebo controlled of metformin and L-citrulline in DMD (NCT01995032)
  • Double blind placebo controlled trial using L-Citrulline in Patients with Post-Polio Syndrome (NCT02801071)
  • Observational trial of muscle function and quantitative muscle MRI in DMD
  • Observational trial of muscle function and quantitative muscle MRI in BMD


    Collaborations

    National Collaborations

    • O. Bieri (Department of Radiology, Division of Radiological Physics, University of Basel)
    • R. Schläger (Department of Neurology, University Hospital Basel, University of Basel)
    • OM. Dorchies (Department of Pharmacology, University of Geneva and University of Lausanne, Geneva)
    • C. Bloetzer (Institute of Social and Preventive Medicine, University of Berne, Berne, Switzerland)
    • Capone (Division of Pediatric Neurology, Children's Hospital, Aarau, Switzerland)
    • Hoffmann-La Roche
    • National patient organisations (Swiss Patient Society of muscle disease patients

    International Collaborations

    • G. Bernert (Department of Pediatrics, Kaiser Franz Josef Hospital, Vienna, Austria)
    • V. Laugel (Department of Pediatric Neurology, Strasbourg University Hospital, Strasbourg, France)
    • N. Gueven (Pharmacy, School of Medicine, University of Tasmania, Hobart, TAS, Australia)
    • M. Hinton (Image Analysis Group, London, UK)
    • D. Tsikas (Core Unit Proteomics, Institute of Toxicology, Hannover Medical School, Carl-Neuberg-Strass, Germany)
    • C. Vuillerot (Hospices Civils de Lyon, Hôpital Femme-Mère-Enfant, L'Escale, Service de Médecine Physique et de Réadaptation Pédiatrique, Bron, France)
    • International patient organisations (Duchenne UK, Duchenne Parent Project Netherlands)

    Ongoing Research Projects

    • Safety, tolerability and efficacy of exogenous ketone bodies for preventive treatment of migraine: A randomised, placebo-controlled, double-blind cross-over study (NCT03132233).
    • Tamoxifen in Duchenne muscular dystrophy: A multicentre, randomised, double-blind, placebo-controlled, phase 3 safety and efficacy 48-week trial (NCT03354039)
    • Ultrasonographic reference values for peripheral nerves and nerve roots in the normal population of children and adolescents

    Research Team

    PD Dr. med. Andrea Klein

    Physician

    Phone +41 61 704 12 12
    Email

    Vanya Gocheva, MSc

    PhD student

    Phone +41 61 704 12 12
    Email

    Dr. med. Sara Nagy, MSc

    Physician

    Phone +41 61 704 12 12
    Email

    Karin Wild

    Clinical Research Coordination and Study Nurse

    Phone +41 61 265 50 78
    Email

    Caroline Baya

    Clinical Research Coordination

    Phone +41 61 704 12 12
    Email

    Dr. med. Patricia Hafner

    Physician

    Phone +41 61 436 54 28
    Email

    Niveditha Putananickal, MSc

    PhD student

    Phone +41 61 704 12 12
    Email

    Dr. med. Cornelia Enzmann

    Physician

    Phone +41 61 704 12 12
    Email

    Dr. med. Bettina Henzi

    Physician

    Phone +41 61 704 12 12
    Email

    Daniela Rubino

    Head of Clinical Research Coordination and Project Management

    Phone +41 61 704 12 12
    Email