Prof. Dr. med.
Raphael Guzman


Chairman Department of Neurosurgery, University Hospital of Basel
Chief Cerebrovascular Neurosurgery
Chief Pediatric Neurosurgery University Children’s Hospital of Basel
Principal Investigator and Group Leader Department of Biomedicine and by courtesy Department of Bioengineering, Basel

University of Basel

+41 61 265 7124



Research Focus


Area of Research


Approved Research Projects

  • Cold-inducible RBM3 in neuroprotection and neurogenesis
  • Therapeutic relevance of stem cells for white matter regeneration in neonatal hypoxia-ischemia
  • Neural progenitor cell migration in the injured brain
  • Stem cell tranplantation in experimental focal strocke: effect of postischemic inflammation on cell survival, differentiation fate and migration
  • Characterization of Telomerase-mediated regulation of EGFR- and BMP/SMAD-signaling essential for proliferation and invasion in human brain tumors.
  • Deciphering Complex Signaling in Disease Using a Next-Generation High-Resolution LC-MS Platform


National Collaborations

  • Inselspital Bern
  • Kantonsspital Luzern
  • Universitätsspital Zürich
  • Kantonsspital Aarau
  • Kantonsspital Chur
  • Hôpitaux Universitaire de Genève
  • Centre hospitalier universitaire Vaudois
  • Instituto di Neuroscienze cliniche deila Svizzera Italiana
  • Hostital du Valais, Kantonsspital Luzern


International Collaborations

  • University of Regensburg (Germany)
  • Stanford University (USA)

Ongoing Research Projects

  • Prediction of Patient-specific Deep Brain Stimulation parameters
  • Development of an electromagnetic tracking system for the implantation for deep brain stimulation electrodes
  • Understanding gut-brain interactions and the effect of dietary measures in obesity and depression: a translational study
  • Laboratory-based phase tomography with micron resolution
  • Early minimally invasive image-guided endoscopic evacuation of intracerebral haemorrhage (EMINENT-ICH): a randomized controlled trial

Research Team