
Prof. Dr. med.
Hendrik Scholl
Position(s)
Head of Department Ophthalmology
Institution
University Hospital Basel
Phone
+41 61 265 90 59
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Research Group Hendrik Scholl
Research Focus
Neurology
Area of Research
Diagnosis and therapy of retinal diseases, especially monogenic and genetically complex macular and retinal degenerations. Outcome measures for intervention studies. Functional (clinical electrophysiology and psychophysics) and morphological (retinal imaging) characterization; Genotype-phenotype correlation
Approved Research Projects
- The ProgStar Study (The Natural History of the Progression of Geographic Atrophy Secondary to Stargardt’s Disease)
- The SMART Study (Scotopic Microperimetric Assessment of Rod Function in Stargardt Disease; ancillary study to the ProgStar Prospective Study)
- The ProgStar-4 Study (The Natural History of the Progression of Atrophy Secondary to Stargardt Disease Type 4 (STGD4): A Prospective Longitudinal Observational Study of STGD4, a PROM1-Related Macular Dystrophy)
- Ocular Albinism: Structure-Function Correlation of the Central Retina, Phenotype-Genotype Correlation and Interventional Therapy to Improve Visual Performance
Collaborations
National Collaborations
- Novartis Institutes for Biomedical Research (NIBR)
- Friedrich Miescher Institute for Biomedical Research, Basel
- OCT research group for OCT technology, Virtual Ophthalmology, Artificial Intelligence (AI) and Robotics of the Department of Ophthalmology at the University of Basel
- Retina Suisse
International Collaborations
- European Network of Clinical Research in Ophthalmology
- Retina International
- PRO RETINA Deutschland e. V.
- Foundation Fighting Blindness
- European Vision Institute EEIG
- ProgStar study group
- Wellcome Trust
- Bertarelli Foundation
- Spectrum Foundation
- Chan Zuckerberg Initiative
- Moorfields Eye Hospital
Ongoing Research Projects
- PINNACLE: Deciphering AMD by deep phenotyping and machine learning
- GABiE: A biomarker evaluation study in patients with geographic atrophy secondary to agerelated macular degeneration (AMD) evaluating the use of microperimetry (fundus-controlled perimetry) and Swept Source-OCT in assessing changes in retinal sensitivity and anatomy over time
- AIRM: A Staged Study Incorporating a Phase 1b, Multicenter, Unmasked, Dose Escalation Evaluation of Safety and Tolerability and a Phase 2, Multicenter, Unmasked, Randomized, Parallel-Group, Controlled, Proof of Concept Investigation of Efficacy and Safety of ASP7317 for Atrophy Secondary to Age-related Macular Degeneration