Prof.
Mascha Binder
Position(s)
Head of Medical Oncology
Institution
University Hospital Basel
Phone +41 61 328 62 90
MD PhD Benjamin Kasenda
Position(s)
Senior Physician
Institution
University Hospital Basel
Phone +41 61 328 50 80
Research Group Mascha Binder / Benjamin Kasenda
Research Focus
Oncology & Hematology
Area of Research
The research group establishes clinical study concepts in the field of oncology with a focus on immunotherapies and novel circulating tumor markers (e.g. tumor DNA). In addition, the group is working on concepts for the pragmatic implementation of study questions that can be integrated into clinical workflows wherever possible (Learning Health Systems).
Approved Research Projects
- FOCUS Study (Immunotherapy Head and Neck Tumors)
- NeoBRAF study (neoadjuvant colon cancer study)
- PherFLOT study (perioperative system therapy in gastric cancer)
- INTEGA study (palliative immunotherapy in HER2 positive gastric cancer patients)
- Swiss Personalized Oncology (SPO) - NDS
Collaborations
National Collaborations
- Prof. Dr. Sai Reddy, ETH Zurich
- Dr. Obinna Chijioke, ETH Zurich
- Dr. Karoline Leuzinger, USB Basel
- PD Dr Lars Hemkens, RC2NB University and University Hospital Basel
- Dr Bram Stieltjes, University Hospital Basel
- PD Dr Matthias Matter, University Hospital Basel
- Dr Noemie Lang, Geneva
- SAKK
International Collaborations
- Prof. Dr. Nicholas Chiorazzi, Feinstein Institutes for Medical Research, New York, United States
- Prof. Dr. Sebastian Kobold, LMU Munich, Germany
- Prof. Dr. Moshe Arditi, Cedars Sinai Los Angeles, United States
- Prof. Dr. Marylyn Addo, UKE Hamburg, Germany
- Prof. Dr. Julian Schulze zur Wiesch, UKE Hamburg, Germany
- Prof. Dr. Ari Waisman, University Medical Center Mainz, Germany
- Dr. Ivona Aksentijevich, NIH Bethesda, United States
- Prof Christopher Fox, Nottingham, UK
- Dr Kate Cwynarski, London, UK
- Prof Dr Gerald Illerhaus, Stuttgart, Germany
- PD Dr Elisabeth Schorb, Freiburg, Germany
Ongoing Research Projects
- Development of IGLV3-21-R110 point mutation-specific CAR T cells for chronic lymphocytic leukemia (CLL)
- Development of novel cell therapies targeting oncogenic B cell receptor (BCR) configurations
- Targeting prohibitins and B cell receptor signaling in CLL
- Optimizing immune checkpoint therapy in Head and Neck, gastric/esophageal and colorectal cancer and overcoming resistance
- Adaptive immune repertoire profiling and analysis in health and disease using machine learning
Research Team
Simon Stücheli, PhD
Research Fellow
Phone -
Email -
Paul Schmidt-Barbo
Doctoral Student
Phone +41 61 325 32 53
Email
Claudia Fischer
Doctoral Student
Phone +41 61 325 32 53
Email