Stephanie Gros

Prof. Dr. med.
Stephanie Gros

Position(s)
Senior Physician Surgery

Institution
University Children's Hospital Basel

Phone +41 61 704 12 12

Email

 

Research Focus

Oncology & Hematology

Area of Research

Mechanisms of tumor proliferation, metastasis and new treatment options in neuroblastoma, cell biology of childhood intestinal disorders


Approved Research Projects

  • Patient tissue evaluation regarding hypoxia-dependent factors (neuroblastoma and rare solid tumors; EKNZ 2015-263)
  • 3D culture, microcalorimetric drug response evaluation and molecular analysis, metastatic potential
  • 3D migration model using neuroblastoma cell and bone marrow-derived MSC compartments
  • Upscaling to a perfused 3D migration model using neuroblastoma cell and bone marrow-derived MSC compartments in a bioreactor
  • Preclinical evaluation of hypoxia-targeted inhibitors in this system
  • Neuroblastoma organoid formation
  • Transmembrane protein-mediated loading of synthetic compartments (SNI project: cooperation with Uni Basel/PSI C. Palivan/R. Kammerer)
  • Improving preoperative image analysis for laparoscopic operability of neuroblastic tumors

Collaborations

National Collaborations

  • Prof. Dr. Ivan Martin, Dr. Manuele Muraro, Tissue Engineering, Department Biomedicine, University of Basel
  • Dr. Uri Nahom, Data Science / Machine Learning Lecturer, UKBB and University of Applied Sciences and Arts Northwestern Switzerland FHNW
  • Prof. Dr. Cornelia Palivan, Department of Chemistry, University of Basel
  • Prof. Dr. Richard Kammerer, Paul Scherrer Institut, Villigen
  • PD Dr. Michael Nash, Department of Chemistry, University of Basel and ETH-DBSSE
  • Dr. Olivier Braissant, Microcalorimetry Unit, Department of Biomedical Engineering, University of Basel
  • Prof. Raphael Guzman, Department of Neurosurgery, Head Pediatric Neurosurgery, University Hospital Basel, University Childrens`Hospital Basel and Department Biomedicine
  • Prof. Dr. Elisabeth Bruder, PD Dr. Thomas Menter, Pathology, University of Basel
  • Pediatric Surgeons Switzerland: Prof. B. Wildhaber (Geneva), Prof. T. Krebs (St. Gallen), PD S. Tahrakan/ Prof. U. Moehrlen (Zürich), Prof. S. Berger (Bern)


International Collaborations

  • Prof. Dr. Claudiu Supuran, NEUROFARBA Department, Sezione di Scienze Farmaceutiche, University of Florence, Italy
  • Dr. rer. nat. Samer Al-Samir, Department of Molecular and Cell Physiology, Hannover Medical School, Hannover
  • Prof. Dr. med. J. R. Izbicki, Department of Surgery, University Medical Center Hamburg Eppendorf
  • PD Dr. med. Jussuf Kaifi MD, Devision of Thoracic Surgery, MU Healthcare, USA
  • Prof. Dr. med. Konrad Reinshagen, Department of Pediatric Surgery, University Medical Center Hamburg Eppendorf
  • Prof. Dr. Robert Hoffman, Anticancer Inc./ Department of Surgery, University of California san Diego, USA
  • Prof. Dr. Klaus Pantel, Department of Tumor Biology, University Medical Center Hamburg Eppendorf
  • Prof. Dr. med. Guido Sauter, Department of Pathology, University Medical Center Hamburg Eppendorf

Ongoing Research Projects

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Research Team

Dr. Zihe Huo, PhD

Research Fellow

Phone +41 61 704 27 75
Email

Dr. med. Remo Bilang

PhD candidate

Phone -
Email

Buyrhan Rashid

Research Fellow

Phone -
Email

Etienne Madörin

Research Fellow

Phone +41 61 704 27 27
Email

Natasha Whitehead, MSc

Research Fellow

Phone -
Email

Stefanie Volkart

Research Fellow

Phone -
Email

Julius Rüth

Research Fellow

Phone -
Email

Piotr Jasko

PhD candidate

Phone -
Email

Rebecca Angresius

Research Fellow

Phone -
Email

Selina Maritz 

Research Fellow

Phone +41 61 704 27 27
Email