Research Focus

Regenerative Medicine & Biomechanics

Area of Research

Facial and cranial malformations, especially cleft lips, jaws and palate:

• Cleft Lip and Palate treatment, in particular approaches to reduce the burden of care, comprising the combined lip and palate repair and machine learning strategies.
• Regenerative medicine strategies by use of scaffolds and cellular components, including from human umbilical cord.
• Advancement of surgical therapies, namely related to precision surgical anatomy, microcirculation and microsurgery.

Burden Reduced Cleft Care and Healing, The Botnar Research Centre for Child Health (www.brc.ch), Multi-Investigator Project 2020-2025: Mueller AA, Solenthaler B, Gross M, Reddy GS, Brudnicki A

National Collaborations
- Dr. Dr. Marcello Augello, Mund-, Kiefer- und Gesichtschirurgie, Kantonsspital Aarau
- Prof. Dr.-Ing. Markus Gross, Computer Graphics Laboratory ETH Zurich & Disney Research Laboratory Zurich
- Dr. sc. Barbara Solenthaler, Simulation and Animation at Computer Graphics Laboratory, ETH Zurich.

International Collaborations
- Assistent Professor Andrzej Brudnicki, Institute of Mother and Child, Department of Surgery of Children and Adolescents, Warsaw, Poland
- Prof. Dr. Bernard Devauchelle, Stomatologie et Chirurgie Maxillo-Faciale & Institute Faire Faces,  Centre Hospitalier Universitaire, Amiens, France
- Prof. Dr.  Srinivas Gosla Reddy, G.S.R. Institute of Craniofacial and Facial Plastic Surgery, Hyderabad, India
- Dr. Bruno Grollemund, Orthopédie Dento-Facial, Centre Hospitalier Régional et Universitaire Strasbourg, France
- Prof. Colin McGuckin, CTIBiotech, Meyzieu Lyon, France
- Dr. Dr. Katinka Kansy, Mund-, Kiefer-, und Gesichtschirurgie, Universitätsklinik und Universität Heidelberg, Deutschland
- Dr. Dr. Jeanette von Jackowski, Mund-, Kiefer- und Gesichtschirurgie, MVZ Lörrach, Deutschland

•  Burden Reduced Cleft Care and Healing
•  Implications from precision surgical anatomy for modern craniofacial paediatrics
•  Presurgical orthopaedics in cleft lip and palate, three dimensional platal shape change and its surgical implication
•  In house manufacturing of an anatomical cleft lip and palate model for education and surgical Training
•  Cephalometric craniofacial growth analysis after combined cleft lip and palate repair with and without primary bone grafting
•  Intraoperative Assessment of the Influence of Cleft Repair on Microcirculation of the Palate
•  Volume stability of secondary alveolar bone grafting