
Prof. Dr. med.
Gian Marco De Marchis
Position(s)
Head of Emergency Neurology Team
Deputy Head Stroke Unit, Neurology & Stroke Center
Attending Physician, Neurology & Stroke Center
Institution
University Hospital Basel
Phone +41 61 328 73 02
Research Group Gian Marco De Marchis
Research Focus
Neurology
Area of Research
Acute cerebrovascular diseases and their management with focus on endovascular treatment and intravenous thrombolysis. Secondary Prevention of Stroke: randomized clinical trials, dyslipidemia, ideal time to start anticoagulant therapy after a stroke. Cohort studies on novel blood markers. Copeptin as first blood marker for prognosis after stroke and TIA. Prehospital stroke care networks to reduce delays. Safety and effectiveness of fast-track vs. open-end hospitalizations.
Approved Research Projects
- AtheroGEnic LipoprotEinS in Ischemic Stroke - The AGELESS Study (Sponsor: Schweizerischer Nationalfond)
- Serum Neurofilaments Light Chain in Acute Ischemic Stroke and Transient Ischemic Attack (cohort study).
- Endovascular Treatment versus Best Medical Treatment for Ischemic Stroke with Large Vessel Occlusion in the 6–24 Hour Window among Non- DAWN-Non-DEFUSE Patients (Study based on the Swiss Stroke Registry)
- Apolipoprotein (B) and Lipoprotein(a) in Patients with Acute Ischemic Stroke
Collaborations
National Collaborations
- Biomarker Signature of Stroke Aetiology Study: The BIOSIGNAL-Study (NCT02274727)
- Midregion Proatrial Natriuretic Peptide to Guide Secondary Stroke Prevention (ongoing, steering committee member, NCT03961334)
- Early versus Late initiation of direct oral Anticoagulants in post-ischaemic stroke patients with atrial fibrillatioN (ELAN, NCT03148457)
- Swiss Atrial Fibrillation Cohort (SWISS AF)
International Collaborations
- Tenecteplase in Wake-Up Stroke Trial (ongoing, steering committee member, NCT03181360)
- PACIFIC-STROKE (ongoing, steering committee member, NCT04304508)
Ongoing Research Projects
- AtheroGEnic LipoprotEinS in Ischemic Stroke - The AGELESS Study (Sponsor: Schweizerischer Nationalfond)
- Endovascular Treatment versus Best Medical Treatment for Ischemic Stroke with Large Vessel Occlusion in the 6–24 Hour Window among Non- DAWN-Non-DEFUSE Patients (Study based on the Swiss Stroke Registry)
- Apolipoprotein (B) and Lipoprotein(a) in Patients with Acute Ischemic Stroke