Investigator-initiated Clinical Trials (IICTs)

Targeted support for academic clinical studies


Clinical researchers pose patient-relevant scientific questions and initiate sponsor-independent clinical trials, thus making an important contribution to medical development.

We support such investigator-initiated clinical trials (IICTs) from conception to publication with a comprehensive range of experts from different disciplines providing consulting and service offers. Here, you will find information on some of the more than 160 ongoing studies that are currently supported by the DKF.

Reference projects

DISTAL

Endovascular therapy for stroke

 

Registration number
still pending

Principal investigator
Research group M. Psychogios, Neurology, and Urs Fischer, Neurology

DKF support
Methodological Consulting, Statistics, Regulatory Affairs, Data Management, Project  Management, Monitoring
 

Funding
SNF IICT

ESTREL

Parkinson drug «Levodopa» for motoric regeneration after stroke

Registration number
NCT03735901

Principal Investigator
Research group S. Engelter, Neurology

DKF support
Methodological Consulting, Statistics, Project Management, Data Managament, Data Science, Monitoring



Funding
SNF IICT

HIT

Correction of the electrolyte balance
 

Registration number
NCT03557957

Principal Investigator
Research Group M. Christ-Crain,Endocrinology, Metabolism and Developmental Disorders

DKF support
Methodological consulting, statistics, data management, monitoring


Funding
SNF IICT

OSPIC

General practitioner study for the therapy of subacute postinfectious cough

Registration number
NCT04232449

Principal investigator
Research group A. Zeller, Immunology & Infectiology

DKF support
Methodological Consulting, Statistics, Regulatory Affairs, Projekt Management, Data Management, On Site Management, Monitoring

Funding
SNF IICT

PREPEC

Quality of life through breast reconstruction with implants after mastectomy

Registration number
NCT04293146

Principal Investigator
Research group W.P. Weber, Breast Centre University Hospital Basel

DKF support
Methodological Consulting, Regulatory Affairs, Data Managament, On Site Management, Monitoring


Funding

SNF IICT

RECUT

Outpatient steroid treatment of COPD patients with acute exacerbation

Registration number
NCT02386735

Principal investigator
Research group J. Leuppi,  Intensive care & Pneumology

DKF support
Statistics, Regulatory Affairs, Data Management, Monitoring



Funding
SNF project funding

BaseTIL

Personalized approach in immunotherapy against skin cancer

Registration number
NCT04165967

Principal investigator
Research group H. Läubli, Oncology & Haematology

DKF support
Statistics, Regulatory Affairs, Project Managament, Data Managament, Data Science, Monitoring


Funding
Innovation Grant USB

SECA

Blood thinner for chronic subdural hematoma

Registration number
NCT03120182

Principal Investigator
Research group J. Solemann, Neurology


DKF support
Statistics, Data Management, Monitoring


Funding

SNF project funding

MechSens

In vivo mechanosensitivity of joint cartilage

Registration number
NCT04128566

Principal Investigator
Research group A. Mündermann, Regenerative Medicine & Biomechanics

DKF support
Methodological Consulting, Statistics, Regulatoriy Affairs

Funding
SNF project funding

CARLO®

Medical technology innovation from Basel: Robot-assisted laser surgery

Registration number
NCT03901209

Principal Investigator
Research group A. Müller, Regenerative Medicine & Biomechanics

DKF support
Statistics, Regulatory Affairs, Data Management, On Site Management, Monitoring

Funding
AOT

KIDS-STEP

Corticosteroids for the treatment of severe pneumonia in children

Registration number
NCT03474991

Principal Investigator
Research group J. van den Anker, Klinische Pharmakologie

DKF support
Methodological Consulting, Statistics, Regulatory Affairs, Data Management, Monitoring

Funding
SNF IICT

Processing of emotions

Neural correlates in social behavior disorders or autism

Registration number
NCT04324099

Prinicipal Investigator
Research group C. Stadler, Psychiatry

DKF support
Methodological Consulting, Statistics, Regulatoriy Affairs


Funding

SNF project funding

APRESCALP

PDE4 inhibitor Apremilast in psoriasis of the scalp
 

Registration number
NCT03553433

Principal Investigator
Research group A. Navarini, Immunology & Infectiology

DKF support
Methodolocical Consulting, Statistics, Regulatory Affairs, Data Mangement, On Site Management, Monitoring


Funding
Cellgene

CoSIP

Copeptin-based test for the differential diagnosis of diabetes insipidus

Registration number
NCT00757276

Principal Investigator
Research group M. Christ-Crain, Endocrinology, Metabolism & Developmental Disorders

DKF support
Statistics, Data Management, Monitoring

Funding
SNF project funding